CG1331 Gene Product From Transcript CG1331-RA (CCP84AF) (AA 1-280) antibody
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- Target
- CG1331 Gene Product From Transcript CG1331-RA (CCP84AF)
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Binding Specificity
- AA 1-280
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
- Application
- ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
- Cross-Reactivity
- Human
- Purification
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Centriolar coiled-coil protein of 110 kDa protein (1-280AA)
- Isotype
- IgG
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- Application Notes
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CG1331 Gene Product From Transcript CG1331-RA (CCP84AF)
- Alternative Name
- CCP11
- Background
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Background: Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425).
Aliases: 110 kDa centrosomal protein antibody, CCP110 antibody, Centriolar coiled coil protein 110 kDa antibody, Centrosomal protein 110 kDa antibody, Centrosomal protein CP110 antibody, Centrosomal protein of 110 kDa antibody, Cep110 antibody, CP110 antibody, CP110_HUMAN antibody, DKFZp781G1416 antibody, FAN antibody, KIAA0419 antibody
- UniProt
- O43303
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