DKK1 antibody (AA 33-266) (Biotin)

Catalog No. ABIN7149879

The Rabbit Polyclonal anti-DKK1 antibody has been validated for ELISA. It is suitable to detect DKK1 in samples from Human.

Quick Overview for DKK1 antibody (AA 33-266) (Biotin) (ABIN7149879)

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DKK1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-DKK1 Antibody (Biotin)

Binding Specificity: AA 33-266

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Dickkopf-related protein 1 protein (33-266AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DKK1

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Alternative Name: DKK1

Background:

Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

Aliases: Dickkopf 1 antibody, Dickkopf 1 homolog antibody, Dickkopf 1 like antibody, Dickkopf homolog 1 antibody, Dickkopf like protein 1 antibody, Dickkopf related protein 1 antibody, Dickkopf WNT signaling pathway inhibitor 1 antibody, Dickkopf-1 antibody, Dickkopf-related protein 1 antibody, DKK 1 antibody, Dkk-1 antibody, Dkk1 antibody, DKK1_HUMAN antibody, hDkk 1 antibody, hDkk-1 antibody, SK antibody

UniProt: O94907

Pathways: WNT Signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation