LRSAM1 antibody (AA 1-290)

Catalog No. ABIN7151057

This Rabbit Polyclonal antibody specifically detects LRSAM1 in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for LRSAM1 antibody (AA 1-290) (ABIN7151057)

Target: LRSAM1 (Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRSAM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-LRSAM1 Antibody

Binding Specificity: AA 1-290

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase LRSAM1 protein (1-290AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LRSAM1

Target: LRSAM1 (Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1))

Alternative Name: LRSAM1

Background:

Background: E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos (PubMed:15256501). Bacterial recognition protein that defends the cytoplasm from invasive pathogens (PubMed:23245322). Localizes to several intracellular bacterial pathogens and generates the bacteria-associated ubiquitin signal leading to autophagy-mediated intracellular bacteria degradation (xenophagy) (PubMed:23245322, PubMed:25484098).

Aliases: CMT2P antibody, E3 ubiquitin protein ligase LRSAM1 antibody, E3 ubiquitin-protein ligase LRSAM1 antibody, EC 6.3.2.- antibody, FLJ31641 antibody, hTAL antibody, Leucine rich repeat and sterile alpha motif containing 1 antibody, Leucine rich repeat and sterile alpha motif containing protein 1 antibody, Leucine-rich repeat and sterile alpha motif-containing protein 1 antibody, LRSAM1 antibody, LRSM1_HUMAN antibody, OTTHUMP00000022174 antibody, OTTHUMP00000022175 antibody, RIFLE antibody, TAL antibody, Tsg101 associated ligase antibody, Tsg101-associated ligase antibody

UniProt: Q6UWE0