PPP1R11 antibody (AA 1-126)

Catalog No. ABIN7151103

The Rabbit Polyclonal anti-PPP1R11 antibody has been validated for ELISA and IHC. It is suitable to detect PPP1R11 in samples from Human.

Quick Overview for PPP1R11 antibody (AA 1-126) (ABIN7151103)

Target: PPP1R11 (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 11 (PPP1R11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R11 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-PPP1R11 Antibody

Binding Specificity: AA 1-126

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase PPP1R11 protein (1-126AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PPP1R11

Target: PPP1R11 (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 11 (PPP1R11))

Alternative Name: PPP1R11

Background:

Background: Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at \\\'Lys-754\\\' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2 (PubMed:27805901). Inhibitor of protein phosphatase 1 (PubMed:9843442).

Aliases: PPP1R11 antibody, HCGV antibody, TCTE5 antibody, E3 ubiquitin-protein ligase PPP1R11 antibody, EC 2.3.2.27 antibody, Hemochromatosis candidate gene V protein antibody, HCG V antibody, Protein phosphatase 1 regulatory subunit 11 antibody, Protein phosphatase inhibitor 3 antibody

UniProt: O60927