TRIM3 antibody (AA 384-472) (HRP)

Catalog No. ABIN7151183

This Rabbit Polyclonal antibody specifically detects TRIM3 in ELISA. It exhibits reactivity toward Human.

Quick Overview for TRIM3 antibody (AA 384-472) (HRP) (ABIN7151183)

Target: TRIM3 (Tripartite Motif Containing 3 (TRIM3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM3 antibody is conjugated to HRP

Application: ELISA

Product Details anti-TRIM3 Antibody (HRP)

Binding Specificity: AA 384-472

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase RNF220 protein (384-472AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TRIM3

Target: TRIM3 (Tripartite Motif Containing 3 (TRIM3))

Alternative Name: RNF22

Background:

Background: E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity). Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling (PubMed:25266658).

Aliases: RNF220 antibody, C1orf164 antibody, E3 ubiquitin-protein ligase RNF220 antibody, EC 2.3.2.27 antibody, RING finger protein 220 antibody, RING-type E3 ubiquitin transferase RNF220 antibody

UniProt: Q5VTB9