UHRF2 antibody (AA 444-585) (HRP)

Catalog No. ABIN7151312

Product Details anti-UHRF2 Antibody (HRP)

Target: UHRF2 (Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))

Binding Specificity: AA 444-585

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UHRF2 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase UHRF2 protein (444-585AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for UHRF2

Target: UHRF2 (Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))

Alternative Name: UHRF2 (UHRF2 Products)

Background:

Background: E3 ubiquitin-protein ligase that is an intermolecular hub protein in the cell cycle network. Through cooperative DNA and histone binding, may contribute to a tighter epigenetic control of gene expression in differentiated cells. Ubiquitinates cyclins, CCND1 and CCNE1, in an apparently phosphorylation-independent manner and induces G1 arrest. Also ubiquitinates PCNP leading to its degradation by the proteasome. E3 SUMO-, but not ubiquitin-, protein ligase for ZNF131.

Aliases: DKFZp434B0920 antibody, DKFZp686G0837 antibody, E3 ubiquitin-protein ligase UHRF2 antibody, MGC33463 antibody, Np95 like RING finger protein antibody, Np95-like ring finger protein antibody, Np95/ICBP90 like RING finger protein antibody, Np95/ICBP90-like RING finger protein antibody, Nuclear protein 97 antibody, Nuclear zinc finger protein Np97 antibody, RING finger protein 107 antibody, RNF 107 antibody, RP11-472F14.2 antibody, Ubiquitin like containing PHD and RING finger domains protein 2 antibody, Ubiquitin-like PHD and RING finger domain-containing protein 2 antibody, Ubiquitin-like-containing PHD and RING finger domains protein 2 antibody, Uhrf2 antibody, UHRF2_HUMAN antibody, URF 2 antibody

UniProt: Q96PU4