ENTPD5 antibody (AA 149-428)

Catalog No. ABIN7151376

The Rabbit Polyclonal anti-ENTPD5 antibody has been validated for WB, ELISA, IHC and IP. It is suitable to detect ENTPD5 in samples from Human.

Quick Overview for ENTPD5 antibody (AA 149-428) (ABIN7151376)

Target: ENTPD5 (Ectonucleoside Triphosphate diphosphohydrolase 5 (ENTPD5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENTPD5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-ENTPD5 Antibody

Binding Specificity: AA 149-428

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Ectonucleoside triphosphate diphosphohydrolase 5 protein (149-428AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ENTPD5

Target: ENTPD5 (Ectonucleoside Triphosphate diphosphohydrolase 5 (ENTPD5))

Alternative Name: ENTPD5

Background:

Background: Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP > IDP > UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.

Aliases: CD39 like 4 antibody, AI196558 antibody, AI987697 antibody, CD39 antigen like 4 antibody, CD39 antigen-like 4 antibody, CD39 like 4 antibody, CD39L4 antibody, Ectonucleoside triphosphate diphosphohydrolase 5 antibody, ENTP5_HUMAN antibody, Entpd5 antibody, ER UDPase antibody, ER-UDPase antibody, GDPase ENTPD5 antibody, Guanosine-diphosphatase ENTPD5 antibody, MGC163357 antibody, MGC163359 antibody, mNTPase antibody, NTPDase 5 antibody, Nucleoside diphosphatase antibody, PCPH antibody, Pcph proto oncogene protein antibody, Proto oncogene CPH antibody, UDPase ENTPD5 antibody, Uridine-diphosphatase ENTPD5 antibody

UniProt: O75356