FAM20C antibody (AA 107-224)

Catalog No. ABIN7152338

This Rabbit Polyclonal antibody specifically detects FAM20C in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for FAM20C antibody (AA 107-224) (ABIN7152338)

Target: FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM20C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-FAM20C Antibody

Binding Specificity: AA 107-224

Purpose: FAM20C Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Extracellular serine/threonine protein kinase FAM20C protein (107-224AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FAM20C

Target: FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))

Alternative Name: FAM20C

Background:

Background: Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth (PubMed:22582013, PubMed:23754375, PubMed:25789606). Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome (PubMed:26091039). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity (PubMed:26091039). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1 (PubMed:22582013, PubMed:25789606). In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion (PubMed:26091039).

Aliases: C76981 antibody, Dentin matrix protein 4 antibody, DKFZp547C074 antibody, DMP-4 antibody, DMP4 antibody, DMP4_HUMAN antibody, Extracellular serine/threonine protein kinase Fam20C antibody, Fam20c antibody, Family with sequence similarity 20 member C antibody, GEF CK antibody, Golgi enriched fraction casein kinase antibody, Protein FAM20C antibody, RNS antibody

UniProt: Q8IXL6