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Fidgetin antibody (AA 132-371)

This Rabbit Polyclonal antibody specifically detects Fidgetin in WB, ELISA, IHC and IF. It exhibits reactivity toward Human.
Catalog No. ABIN7152932

Quick Overview for Fidgetin antibody (AA 132-371) (ABIN7152932)

Target

Fidgetin (FIGN)

Reactivity

  • 17
  • 10
Human

Host

  • 16
  • 1
Rabbit

Clonality

  • 16
  • 1
Polyclonal

Conjugate

  • 8
  • 3
  • 2
  • 2
  • 1
  • 1
This Fidgetin antibody is un-conjugated

Application

  • 13
  • 12
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Binding Specificity

    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    AA 132-371

    Cross-Reactivity

    Human, Mouse

    Purification

    >95%, Protein G purified

    Immunogen

    Recombinant Human Fidgetin protein (132-371AA)

    Isotype

    IgG
  • Application Notes

    Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    Fidgetin (FIGN)

    Alternative Name

    FIGN

    Background

    Background: ATP-dependent microtubule severing protein. Severs microtubules along their length and depolymerizes their ends, primarily the minus-end, that may lead to the suppression of microtubule growth from and attachment to centrosomes. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome.

    Aliases: FIGNFidgetin antibody

    UniProt

    Q5HY92
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