Fukutin antibody (AA 87-276) (Biotin)
Quick Overview for Fukutin antibody (AA 87-276) (Biotin) (ABIN7153228)
Target
See all Fukutin (FKTN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 87-276
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Fukutin protein (87-276AA)
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Fukutin (FKTN)
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Alternative Name
- FKTN
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Background
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Background: Glycosyltransferase involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes. Could be involved in brain development.
Aliases: CMD1X antibody, FCMD antibody, FCMD gene antibody, FKTN antibody, FKTN_HUMAN antibody, Fukutin antibody, Fukuyama type congenital muscular dystrophy protein antibody, Fukuyama-type congenital muscular dystrophy protein antibody, LGMD2M antibody, MDDGA4 antibody, MDDGB4 antibody, MDDGC4 antibody, MGC126857 antibody, MGC134944 antibody, MGC134945 antibody, MGC138243 antibody, OTTHUMP00000021841 antibody, patient fukutin antibody
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UniProt
- O75072
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Pathways
- Regulation of Carbohydrate Metabolic Process
Target
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