GRHL1 antibody (AA 1-95) (Biotin)

Catalog No. ABIN7154373

The Rabbit Polyclonal anti-GRHL1 antibody has been validated for ELISA. It is suitable to detect GRHL1 in samples from Human.

Quick Overview for GRHL1 antibody (AA 1-95) (Biotin) (ABIN7154373)

Target: GRHL1 (Grainyhead-Like 1 (GRHL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRHL1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-GRHL1 Antibody (Biotin)

Binding Specificity: AA 1-95

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Grainyhead-like protein 1 homologprotein (1-95AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GRHL1

Target: GRHL1 (Grainyhead-Like 1 (GRHL1))

Alternative Name: GRHL1

Background:

Background: Transcription factor involved in epithelial development. Binds directly to the consensus DNA sequence 5\'-AACCGGTT-3\' (PubMed:12175488, PubMed:18288204). Important regulator of DSG1 in the context of hair anchorage and epidermal differentiation, participates in the maintenance of the skin barrier. There is no genetic interaction with GRHL3, no functional cooperativity due to diverse target gene selectivity during epithelia development (By similarity). Isoform 1 may function as an activator and isoform 2 as a repressor in tissues where both forms are expressed (PubMed:12175488).

Aliases: Grainyhead-like protein 1 homolog antibody, grhl1 antibody, GRHL1_HUMAN antibody, LBP32 antibody, Mammalian grainyhead antibody, MGR antibody, NH32 antibody, TFCP2L2 antibody, Transcription factor CP2-like 2 antibody, Transcription factor LBP-32 antibody

UniProt: Q9NZI5

Pathways: Regulation of Lipid Metabolism by PPARalpha