HDAC5 antibody (AA 1-100) (Biotin)

Catalog No. ABIN7155319

This anti-HDAC5 antibody is a Rabbit Polyclonal antibody detecting HDAC5 in ELISA. Suitable for Human.

Quick Overview for HDAC5 antibody (AA 1-100) (Biotin) (ABIN7155319)

Target: HDAC5 (Histone Deacetylase 5 (HDAC5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC5 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-HDAC5 Antibody (Biotin)

Binding Specificity: AA 1-100

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Histone deacetylase 5 protein (1-100AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HDAC5

Target: HDAC5 (Histone Deacetylase 5 (HDAC5))

Alternative Name: HDAC5

Background:

Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

Aliases: Antigen NY CO 9 antibody, Antigen NY-CO-9 antibody, HD5 antibody, HDAC 5 antibody, HDAC5 antibody, HDAC5_HUMAN antibody, Histone deacetylase 5 antibody, NY CO 9 antibody

UniProt: Q9UQL6

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process