IGKC antibody (AA 1-107) (FITC)

Catalog No. ABIN7156096

This anti-IGKC antibody is a Rabbit Polyclonal antibody detecting IGKC in . Suitable for Human.

Quick Overview for IGKC antibody (AA 1-107) (FITC) (ABIN7156096)

Target: IGKC (Immunoglobulin kappa Constant (IGKC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGKC antibody is conjugated to FITC

Application: Please inquire

Product Details anti-IGKC Antibody (FITC)

Binding Specificity: AA 1-107

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Immunoglobulin kappa constant protein (1-107AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IGKC

Target: IGKC (Immunoglobulin kappa Constant (IGKC))

Alternative Name: IGKC

Background:

Background: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).

Aliases: IGKCImmunoglobulin kappa constant antibody, Ig kappa chain C region antibody, Ig kappa chain C region AG antibody, Ig kappa chain C region CUM antibody, Ig kappa chain C region EU antibody, Ig kappa chain C region OU antibody, Ig kappa chain C region ROY antibody, Ig kappa chain C region TI antibody

UniProt: P01834