KLF4 antibody (AA 30-230)

Catalog No. ABIN7157727

The Rabbit Polyclonal anti-KLF4 antibody has been validated for WB, ELISA and IHC. It is suitable to detect KLF4 in samples from Human.

Quick Overview for KLF4 antibody (AA 30-230) (ABIN7157727)

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-KLF4 Antibody

Binding Specificity: AA 30-230

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Krueppel-like factor 4 protein (30-230AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for KLF4

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Alternative Name: KLF4

Background:

Background: Transcription factor, can act both as activator and as repressor. Binds the 5\\\'-CACCC-3\\\' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

Aliases: Endothelial Kruppel like zinc finger protein antibody, Epithelial zinc finger protein EZF antibody, EZF antibody, GKLF antibody, gut Kruppel-like factor antibody, Gut-enriched krueppel-like factor antibody, KLF antibody, KLF4 antibody, KLF4_HUMAN antibody, Krueppel-like factor 4 antibody, Kruppel like factor 4 (Epithelial zinc finger protein EZF) (Gut enriched Krueppel like factor) antibody, Kruppel like factor 4 (gut) antibody

UniProt: O43474

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance