STEAP1 antibody (AA 3-69)

Catalog No. ABIN7159501

The Rabbit Polyclonal anti-STEAP1 antibody (ABIN7159501) specifically detects STEAP1 in WB, ELISA, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for STEAP1 antibody (AA 3-69) (ABIN7159501)

Target: STEAP1 (Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STEAP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-STEAP1 Antibody

Binding Specificity: AA 3-69

Purpose: STEAP1 Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Metalloreductase STEAP1 protein (3-69AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for STEAP1

Target: STEAP1 (Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1))

Alternative Name: STEAP1

Background:

Background: E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis By similarity. Mediates \\\'Lys-63\\\'-linked polyubiquitination of TBK1, which probably participates in kinase activation.

Aliases: 2410007B19Rik antibody, EC 1.16.1.- antibody, Metalloreductase STEAP1 antibody, MGC19484 antibody, PRSS 24 antibody, PRSS24 antibody, Six transmembrane epithelial antigen of prostate antibody, Six transmembrane epithelial antigen of the prostate 1 antibody, Six transmembrane epithelial antigen of the prostate antibody, Six-transmembrane epithelial antigen of prostate 1 antibody, STEA1_HUMAN antibody, STEAP 1 antibody, Steap antibody, STEAP1 antibody

UniProt: Q9UHE8

Pathways: Transition Metal Ion Homeostasis