MEGF10 antibody (AA 123-314) (HRP)

Catalog No. ABIN7160334

The Rabbit Polyclonal anti-MEGF10 antibody has been validated for ELISA. It is suitable to detect MEGF10 in samples from Human.

Quick Overview for MEGF10 antibody (AA 123-314) (HRP) (ABIN7160334)

Target: MEGF10 (Multiple EGF-Like-Domains 10 (MEGF10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEGF10 antibody is conjugated to HRP

Application: ELISA

Product Details anti-MEGF10 Antibody (HRP)

Binding Specificity: AA 123-314

Purpose: MEGF10 Antibody, HRP conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Multiple epidermal growth factor-like domains protein 10 protein (123-314AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MEGF10

Target: MEGF10 (Multiple EGF-Like-Domains 10 (MEGF10))

Alternative Name: MEGF10

Background:

Background: Membrane receptor involved in phagocytosis by macrophages of apoptotic cells. Cooperates with ABCA1 within the process of engulfment. Promotes the formation of large intracellular vacuoles and may be responsible for the uptake of amyloid-beta peptides. May also function in the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements. May play role in cell adhesion and motility. Is also an essential factor in the regulation of myogenesis. Controls the balance between skeletal muscle satellite cells proliferation and differentiation problably through regulation of the notch signaling pathway.

Aliases: MEGF10 antibody, KIAA1780Multiple epidermal growth factor-like domains protein 10 antibody, Multiple EGF-like domains protein 10 antibody

UniProt: Q96KG7

Pathways: Regulation of Muscle Cell Differentiation