OPRL1 antibody (AA 323-370)

Catalog No. ABIN7161665

This Rabbit Polyclonal antibody specifically detects OPRL1 in WB, ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for OPRL1 antibody (AA 323-370) (ABIN7161665)

Target: OPRL1 (Opiate Receptor-Like 1 (OPRL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPRL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-OPRL1 Antibody

Binding Specificity: AA 323-370

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Nociceptin receptor protein (323-370AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IF:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for OPRL1

Target: OPRL1 (Opiate Receptor-Like 1 (OPRL1))

Alternative Name: OPRL1

Background:

Background: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.

Aliases: H.sapiens mRNA for ORL1 receptor antibody, Kappa type 3 opioid receptor antibody, Kappa-type 3 opioid receptor antibody, kappa3-related opioid receptor antibody, KOR 3 antibody, KOR-3 antibody, KOR3 antibody, LC132 receptor like antibody, LC132 receptor, rat, homolog of antibody, MGC34578 antibody, Nociceptin receptor antibody, Nociceptin/orphanin FQ (N/OFQ) peptide receptor antibody, NOCIR antibody, NOP antibody, OOR antibody, Opiate receptor like 1 antibody, Opiod receptor like 1 antibody, Oprl1 antibody, OPRX_HUMAN antibody, ORL1 antibody, Orphanin FQ receptor antibody

UniProt: P41146