Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

SMARCA2 antibody (AA 700-1216) (HRP)

SMARCA2 Reactivity: Human ELISA Host: Rabbit Polyclonal HRP
Catalog No. ABIN7164524
$328.90
Plus shipping costs $45.00
Shipping to: United States
Delivery in 10 to 13 Business Days
  • Target See all SMARCA2 Antibodies
    SMARCA2 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2))
    Binding Specificity
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 700-1216
    Reactivity
    • 36
    • 20
    • 19
    • 9
    • 9
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    Human
    Host
    • 31
    • 3
    • 1
    • 1
    Rabbit
    Clonality
    • 32
    • 4
    Polyclonal
    Conjugate
    • 26
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMARCA2 antibody is conjugated to HRP
    Application
    • 25
    • 12
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Probable global transcription activator SNF2L2 protein (700-1216AA)
    Isotype
    IgG
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SMARCA2 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2))
    Alternative Name
    SMARCA2 (SMARCA2 Products)
    Synonyms
    BAF190 antibody, BRM antibody, NCBRS antibody, SNF2 antibody, SNF2L2 antibody, SNF2LA antibody, SWI2 antibody, Sth1p antibody, hBRM antibody, hSNF2a antibody, brm antibody, 2610209L14Rik antibody, SNF2alpha antibody, Snf2l2 antibody, brahma antibody, psa-4 antibody, wu:fa56c07 antibody, wu:fi27f11 antibody, zgc:66238 antibody, Brahma antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 L homeolog antibody, SMARCA2 antibody, smarca2.L antibody, Smarca2 antibody, smarca2 antibody
    Background

    Background: Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.

    Aliases: ATP dependent helicase SMARCA2 antibody, ATP-dependent helicase SMARCA2 antibody, BAF190 antibody, BAF190B antibody, BRG1-associated factor 190B antibody, BRM antibody, FLJ36757 antibody, Global transcription activator homologous sequence antibody, hBRM antibody, hSNF2a antibody, MGC74511 antibody, Possible global transcription activator SNF2L2 antibody, Probable global transcription activator SNF2L2 antibody, Protein brahma homolog antibody, SMARCA2 antibody, SMCA2_HUMAN antibody, SNF2 alpha antibody, SNF2 like 2 antibody, SNF2-alpha antibody, SNF2/SWI2 like protein 2 antibody, SNF2L2 antibody, SNF2LA antibody, Sth1p antibody, Sucrose nonfermenting 2 like protein 2 antibody, SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 2 antibody, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 antibody

    UniProt
    P51531
You are here: