SMARCA2 antibody (Middle Region)

Catalog No. ABIN927492

Product Details anti-SMARCA2 Antibody

Target: SMARCA2 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Chicken, Zebrafish (Danio rerio), Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMARCA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine), Zebrafish (Brachydanio rerio), Cow (Bovine), Frog, Chicken

Purification: Purified

Immunogen: SMARCA2 antibody was raised in rabbit using the middle region of SMARCA2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

SMARCA2 Blocking Peptide, catalog no. 33R-9606, is also available for use as a blocking control in assays to test for specificity of this SMARCA2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for SMARCA2

Target: SMARCA2 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2))

Alternative Name: SMARCA2 (SMARCA2 Products)

Synonyms: BAF190 antibody, BRM antibody, NCBRS antibody, SNF2 antibody, SNF2L2 antibody, SNF2LA antibody, SWI2 antibody, Sth1p antibody, hBRM antibody, hSNF2a antibody, brm antibody, 2610209L14Rik antibody, SNF2alpha antibody, Snf2l2 antibody, brahma antibody, psa-4 antibody, wu:fa56c07 antibody, wu:fi27f11 antibody, zgc:66238 antibody, Brahma antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 L homeolog antibody, SMARCA2 antibody, smarca2.L antibody, Smarca2 antibody, smarca2 antibody

Background: SMARCA2 is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. Synonyms: Polyclonal SMARCA2 antibody, Anti-SMARCA2 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 antibody.