PTGDS antibody (AA 23-190)

Catalog No. ABIN7164874

Product Details anti-PTGDS Antibody

Target: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Binding Specificity: AA 23-190

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGDS antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Prostaglandin-H2 D-isomerase protein (23-190AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PTGDS

Target: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Alternative Name: PTGDS (PTGDS Products)

Synonyms: 6PGD antibody, GSTS antibody, GSTS1-1 antibody, PGD2 antibody, PGDS antibody, L-PGDS antibody, LPGDS antibody, PDS antibody, PGDS2 antibody, H-PGDS antibody, Ptgds2 antibody, 21kDa antibody, Ptgs3 antibody, PH2DISO antibody, phosphogluconate dehydrogenase antibody, hematopoietic prostaglandin D synthase antibody, prostaglandin D2 synthase antibody, prostaglandin D2 synthase (brain) antibody, prostaglandin D synthase antibody, prostaglandin D2 synthase 21kDa (brain) antibody, PGD antibody, HPGDS antibody, PTGDS antibody, Hpgds antibody, Ptgds antibody, LOC100009453 antibody

Background:

Background: Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.

Aliases: Beta trace protein antibody, Beta-trace protein antibody, Cerebrin 28 antibody, Cerebrin-28 antibody, glutathione independent PGD synthase antibody, Glutathione independent PGD synthetase antibody, Glutathione-independent PGD synthase antibody, L PGDS antibody, Lipocalin type prostaglandin D synthase antibody, Lipocalin-type prostaglandin-D synthase antibody, LPGDS antibody, PDS antibody, PGD2 antibody, PGD2 synthase antibody, PGDS antibody, PGDS2 antibody, prostaglandin D synthase antibody, prostaglandin D2 synthase (21 kDa, brain) antibody, prostaglandin D2 synthase (brain) antibody, prostaglandin D2 synthase 21 kDa (brain) antibody, Prostaglandin D2 synthase antibody, prostaglandin H2 D isomerase antibody, Prostaglandin-D2 synthase antibody, Prostaglandin-H2 D-isomerase antibody, PTGDS antibody, PTGDS_HUMAN antibody, RP23-47P18.11-006 antibody

UniProt: P41222