PTGDS antibody (N-Term)

Catalog No. ABIN2783496

The Rabbit Polyclonal anti-PTGDS antibody (ABIN2783496) specifically detects PTGDS in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Dog, Horse, Rabbit, Guinea Pig and Cow samples.

Quick Overview for PTGDS antibody (N-Term) (ABIN2783496)

Target: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Guinea Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGDS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PTGDS Antibody

Binding Specificity: N-Term

Purpose: PGDS Antibody - N-terminal region

Sequence: EQADWPEIKS TLPFGKIPIL EVDGLTLHQS LAIARYLTKN TDLAGNTEME

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PGDS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PGDS

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48763-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PTGDS

Target: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Alternative Name: PGDS

Background:

Background Information: PGDS is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes. Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Hematopoietic prostaglandin D synthase

Alternative Symbols: GSTS, PGD2, PGDS, GSTS1, GSTS1-1

Protein Name: Hematopoietic prostaglandin D synthase

Molecular Weight: 23kDa

Gene ID: 27306

NCBI Accession: NP_055300

UniProt: O60760