MEMO1 antibody (AA 1-297)
Quick Overview for MEMO1 antibody (AA 1-297) (ABIN7165806)
Target
See all MEMO1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-297
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Cross-Reactivity
- Human
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Purification
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Protein MEMO1 protein (1-297AA)
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Isotype
- IgG
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Application Notes
- Recommended dilution: IHC:1:20-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MEMO1 (Mediator of Cell Motility 1 (MEMO1))
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Alternative Name
- MEMO1
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Background
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Background: May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.
Aliases: C21orf19-like protein antibody, C2orf4 antibody, CGI 27 antibody, DKFZp434I0135 antibody, FLJ25031 antibody, HCV NS5A-transactivated protein 7 antibody, Hepatitis C virus NS5A-transactivated protein 7 antibody, Mediator of cell motility 1 antibody, Mediator of ErbB2-driven cell motility 1 antibody, MEMO antibody, Memo-1 antibody, memo1 antibody, MEMO1_HUMAN antibody, NS5ATP7 antibody, Protein MEMO1 antibody
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UniProt
- Q9Y316
Target
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