PPM1A antibody (AA 1-382)

Catalog No. ABIN7165941

The Rabbit Polyclonal anti-PPM1A antibody has been validated for WB, ELISA and IHC. It is suitable to detect PPM1A in samples from Human.

Quick Overview for PPM1A antibody (AA 1-382) (ABIN7165941)

Target: PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPM1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PPM1A Antibody

Binding Specificity: AA 1-382

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Protein phosphatase 1A protein (1-382AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PPM1A

Target: PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))

Alternative Name: PPM1A

Background:

Background: Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.

Aliases: Protein phosphatase 2C isoform alpha antibody, EC 3.1.3.16 antibody, FLJ42306 antibody, IA antibody, MGC9201 antibody, Mpp alpha antibody, PP2C alpha antibody, PP2C-alpha antibody, PP2CA antibody, PP2Calpha antibody, PPM 1A antibody, PPM1A antibody, PPM1A_HUMAN antibody, PPPM1A antibody, Protein phosphatase 1A (formerly 2C) magnesium dependent alpha isoform antibody, Protein phosphatase 1A antibody, Protein phosphatase 1A magnesium dependent alpha antibody, Protein phosphatase 2C alpha antibody, Protein phosphatase 2C alpha isoform antibody, Protein phosphatase 2C isoform alpha antibody, Protein phosphatase IA antibody, Protein phosphatase, Mg2+/Mn2+ dependent, 1A antibody

UniProt: P35813