RUFY3 antibody (AA 243-352) (Biotin)

Catalog No. ABIN7166027

This Rabbit Polyclonal antibody specifically detects RUFY3 in ELISA. It exhibits reactivity toward Human.

Quick Overview for RUFY3 antibody (AA 243-352) (Biotin) (ABIN7166027)

Target: RUFY3 (RUN and FYVE Domain Containing 3 (RUFY3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUFY3 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-RUFY3 Antibody (Biotin)

Binding Specificity: AA 243-352

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein RUFY3 protein (243-352AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RUFY3

Target: RUFY3 (RUN and FYVE Domain Containing 3 (RUFY3))

Alternative Name: RUFY3

Background:

Background: Plays a role in the generation of neuronal polarity formation and axon growth (By similarity). Implicated in the formation of a single axon by developing neurons (By similarity). May inhibit the formation of additional axons by inhibition of PI3K in minor neuronal processes (By similarity). Plays a role in the formation of F-actin-enriched protrusive structures at the cell periphery (PubMed:25766321). Plays a role in cytoskeletal organization by regulating the subcellular localization of FSCN1 and DBN1 at axonal growth cones (By similarity). Promotes gastric cancer cell migration and invasion in a PAK1-dependent manner (PubMed:25766321).

Aliases: Protein RUFY3 antibody, rap2 interacting protein x antibody, Rap2 interacting protein x isoform 2 antibody, Rap2-interacting protein x antibody, RIPx antibody, Rpipx antibody, Rufy3 antibody, RUFY3_HUMAN antibody, RUN and FYVE domain containing 3 antibody, Singar antibody, Singar1 antibody, Single axon regulated protein antibody, single axon related 1 antibody, Single axon-regulated protein antibody

UniProt: Q7L099