Degenerin Unc-8 (UNC-8) (AA 124-388) antibody (HRP)

Catalog No. ABIN7166268

Product Details

Target: Degenerin Unc-8 (UNC-8)

Binding Specificity: AA 124-388

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein unc-80 homolog protein (124-388AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: Degenerin Unc-8 (UNC-8)

Alternative Name: UNC8

Background:

Background: Component of the NALCN sodium channel complex, required for channel regulation. This complex is a cation channel activated by neuropeptides substance P, neurotensin, and extracellular calcium that regulates neuronal excitability by controlling the sizes of NALCN-dependent sodium-leak current. UNC80 is essential for NALCN sensitivity to extracellular calcium.

Aliases: C2orf21 antibody, Protein unc-80 homolog antibody, UNC 80 antibody, Unc 80 homolog (C. elegans) antibody, Unc80 antibody, UNC80_HUMAN antibody

UniProt: Q8N2C7