RGS2 antibody (AA 1-241)

Catalog No. ABIN7167605

This Rabbit Polyclonal antibody specifically detects RGS2 in ELISA, WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for RGS2 antibody (AA 1-241) (ABIN7167605)

Target: RGS2 (Regulator of G-Protein Signaling 2 (RGS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-RGS2 Antibody

Binding Specificity: AA 1-241

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Regulator of G-protein signaling 20 protein (1-241AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RGS2

Target: RGS2 (Regulator of G-Protein Signaling 2 (RGS2))

Alternative Name: RGS2

Background:

Background: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds selectively to G(z)-alpha and G(alpha)-i2 subunits, accelerates their GTPase activity and regulates their signaling activities. The G(z)-alpha activity is inhibited by the phosphorylation and palmitoylation of the G-protein. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins.

Aliases: G(z)GAP antibody, Gz selective GTPase activating protein antibody, Gz-GAP antibody, Gz-selective GTPase-activating protein antibody, HGNC:14600 antibody, Regulator of G protein signaling 20 antibody, Regulator of G-protein signaling 20 antibody, Regulator of G-protein signaling Z1 antibody, Regulator of Gz selective protein signaling 1 antibody, Regulator of Gz-selective protein signaling 1 antibody, RGS20 antibody, RGS20_HUMAN antibody, RGSZ1 antibody, ZGAP1 antibody

UniProt: O76081

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation