SCARA5 antibody (AA 303-428)

Catalog No. ABIN7168610

This Rabbit Polyclonal antibody specifically detects SCARA5 in ELISA, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for SCARA5 antibody (AA 303-428) (ABIN7168610)

Target: SCARA5 (Scavenger Receptor Class A, Member 5 (SCARA5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCARA5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SCARA5 Antibody

Binding Specificity: AA 303-428

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Scavenger receptor class A member 5 protein (303-428AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SCARA5

Target: SCARA5 (Scavenger Receptor Class A, Member 5 (SCARA5))

Alternative Name: SCARA5

Background:

Background: Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1).

Aliases: FLJ23907 antibody, MGC45780 antibody, NET33 antibody, SCAR5_HUMAN antibody, SCARA 5 antibody, scara5 antibody, Scavenger receptor class A member 5 antibody, Scavenger receptor class A, member 5 (putative) antibody, Scavenger receptor class A, member 5 antibody, Scavenger receptor hlg antibody, Tesr antibody, Testis expressed scavenger receptor antibody

UniProt: Q6ZMJ2

Pathways: Transition Metal Ion Homeostasis