STAM2 antibody (AA 376-525)

Catalog No. ABIN7169694

Product Details anti-STAM2 Antibody

Target: STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))

Binding Specificity: AA 376-525

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAM2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Signal transducing adapter molecule 2 protein (376-525AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for STAM2

Target: STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))

Alternative Name: STAM2 (STAM2 Products)

Background:

Background: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).

Aliases: DKFZp564C047 antibody, Hbp antibody, Hrs-binding protein antibody, HSE1 homolog antibody, Signal transducing adapter molecule 2 antibody, Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 antibody, Signal transducing adaptor molecule 2A antibody, Signal transducing adaptor molecule 2B antibody, Signal transducing adaptor molecule antibody, STAM like protein containing SH3 and ITAM domains 2 antibody, STAM-2 antibody, Stam2 antibody, STAM2_HUMAN antibody, STAM2A antibody, STAM2B antibody

UniProt: O75886

Pathways: EGFR Signaling Pathway, EGFR Downregulation