STAM2 antibody (AA 376-525)

Catalog No. ABIN6148550

Product Details anti-STAM2 Antibody

Target: STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))

Binding Specificity: AA 376-525

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: KLHPPAHYPP ASSGVPMQTY PVQSHGGNYM GQSIHQVTVA QSYSLGPDQI GPLRSLPPNV NSSVTAQPAQ TSYLSTGQDT VSNPTYMNQN SNLQSATGTT AYTQQMGMSV DMSSYQNTTS NLPQLAGFPV TVPAHPVAQQ HTNYHQQPLL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 376-525 of human STAM2 (NP_005834.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for STAM2

Target: STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))

Alternative Name: STAM2 (STAM2 Products)

Synonyms: Hbp antibody, STAM2A antibody, STAM2B antibody, 1200004O12Rik antibody, 5730456G07Rik antibody, BB145015 antibody, stam2 antibody, MGC52950 antibody, zgc:103628 antibody, signal transducing adaptor molecule 2 antibody, signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 antibody, signal transducing adaptor molecule 2 S homeolog antibody, STAM2 antibody, Stam2 antibody, stam2.S antibody, stam2 antibody

Background: The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.,STAM2,Hbp,STAM2A,STAM2B,Signal Transduction,STAM2

Molecular Weight: 38 kDa/58 kDa

Gene ID: 10254

UniProt: O75886

Pathways: EGFR Signaling Pathway, EGFR Downregulation