SF3B3 antibody (AA 948-1217)

Catalog No. ABIN7170623

This Rabbit Polyclonal antibody specifically detects SF3B3 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for SF3B3 antibody (AA 948-1217) (ABIN7170623)

Target: SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3B3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-SF3B3 Antibody

Binding Specificity: AA 948-1217

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Splicing factor 3B subunit 3 protein (948-1217AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SF3B3

Target: SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))

Alternative Name: SF3B3

Background:

Background: Subunit of the splicing factor SF3B required for \\\'A\\\' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the \\\'E\\\' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.

Aliases: KIAA0017 antibody, Pre mRNA splicing factor SF3b 130 kDa subunit antibody, Pre-mRNA-splicing factor SF3b 130 kDa subunit antibody, RSE1 antibody, SAP 130 antibody, SAP130 antibody, SF3b130 antibody, SF3B3 antibody, SF3B3_HUMAN antibody, Spliceosome associated protein 130 antibody, Spliceosome-associated protein 130 antibody, Splicing factor 3b subunit 3 130kD antibody, Splicing factor 3B subunit 3 antibody, STAF130 antibody

UniProt: Q15393