Splicing factor U2AF 26 kDa subunit (U2AF1L4) (AA 1-202) antibody

Catalog No. ABIN7170630

The Rabbit Polyclonal anti-not_set antibody has been validated for ELISA and IHC. It is suitable to detect not_set in samples from Human.

Quick Overview for Splicing factor U2AF 26 kDa subunit (U2AF1L4) (AA 1-202) antibody (ABIN7170630)

Target: Splicing factor U2AF 26 kDa subunit (U2AF1L4)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details

Binding Specificity: AA 1-202

Purpose: U2AF1L4 Antibody

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Splicing factor U2AF 26 kDa subunit protein (1-202AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: Splicing factor U2AF 26 kDa subunit (U2AF1L4)

Alternative Name: U2AF1L4

Background:

Background: RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3\\\'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation, an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3\\\'-splice site (By similarity). Shows a preference for AGC or AGA (By similarity).

Aliases: FLJ35525 antibody, MGC33901 antibody, Splicing factor U2AF 26 kDa subunit antibody, U2 auxiliary factor 26 antibody, U2 small nuclear RNA auxiliary factor 1 like 3 antibody, U2 small nuclear RNA auxiliary factor 1 like 4 antibody, U2 small nuclear RNA auxiliary factor 1 like protein 3 antibody, U2 small nuclear RNA auxiliary factor 1 like protein 4 antibody, U2 small nuclear RNA auxiliary factor 1-like protein 3 antibody, U2 small nuclear RNA auxiliary factor 1-like protein 4 antibody, U2(RNU2) small nuclear RNA auxiliary factor 1 like 3 antibody, U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3 antibody, U2AF1 like protein 3 antibody, U2AF1 RS3 antibody, U2AF1-like protein 3 antibody, U2AF1L3V1 antibody, U2AF1L4 antibody, U2AF1RS3 antibody, U2af26 antibody, U2AF4_HUMAN antibody, U2RNU2 small nuclear RNA auxiliary factor 1 like 3 antibody, U2RNU2 small nuclear RNA auxiliary factor 1 like protein 3 antibody

UniProt: Q8WU68