CYP17A1 antibody (AA 1-508)

Catalog No. ABIN7170749

Product Details anti-CYP17A1 Antibody

Target: CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))

Binding Specificity: AA 1-508

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP17A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Steroid 17-alpha-hydroxylase/17,20 lyase protein (1-508AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CYP17A1

Target: CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))

Alternative Name: CYP17A1 (CYP17A1 Products)

Background:

Background: Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.

Aliases: 20 lyase antibody, CP17A_HUMAN antibody, CPT7 antibody, CYP17 antibody, CYP17A1 antibody, CYPXVII antibody, Cytochrome P450 17A1 antibody, Cytochrome P450 family 17 antibody, Cytochrome P450 family 17 subfamily A polypeptide 1 antibody, Cytochrome p450 subfamily XVII (steroid 17 alpha hydroxylase) adrenal hyperplasia antibody, Cytochrome p450 XVIIA1 antibody, Cytochrome P450-C17 antibody, Cytochrome P450c17 antibody, OTTHUMP00000020382 antibody, P450 C17 antibody, P450c17 antibody, S17AH antibody, Steroid 17 alpha hydroxylase/17,20 lyase antibody, Steroid 17 alpha monooxygenase antibody, Steroid 17-alpha-hydroxylase/17 antibody, Steroid 17-alpha-monooxygenase antibody

UniProt: P05093

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin