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CYP17A1 antibody (Center)

CYP17A1 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855475
  • Target See all CYP17A1 Antibodies
    CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))
    Binding Specificity
    • 12
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 44
    • 21
    • 21
    Human, Mouse
    Host
    • 47
    • 3
    • 1
    Rabbit
    Clonality
    • 44
    • 7
    Polyclonal
    Conjugate
    • 27
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP17A1 antibody is un-conjugated
    Application
    • 43
    • 22
    • 12
    • 11
    • 10
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Chimpanzee
    Cross-Reactivity (Details)
    Chimpanzee (100 %)
    Characteristics
    Rabbit Polyclonal antibody to CYP17A1 (cytochrome P450, family 17, subfamily A, polypeptide 1)
    CYP17A1 antibody [N1C2]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human CYP17A1. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product CYP17A1 Primary Antibody
  • Application Notes
    Suggested dilution Reference Western blot 1:500-1:20000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:20000*
    Comment

    Positive Control: NIH-3T3 , C2C12 , MCF-7 , HepG2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.65 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))
    Alternative Name
    CYP17A1 (CYP17A1 Products)
    Synonyms
    cyp17 antibody, CYPXVII antibody, P450c17 antibody, cyp17a1 antibody, P450-C17 antibody, wu:fi13g04 antibody, wu:fi17b11 antibody, wu:fi31c08 antibody, zgc:136516 antibody, zgc:66494 antibody, P45017A1 antibody, CYP17 antibody, CPT7 antibody, P450C17 antibody, S17AH antibody, Cyp17 antibody, p450c17 antibody, cytochrome P450 17A1 antibody, cytochrome P450, family 17, subfamily A, polypeptide 1 antibody, steroidogenic cytochrome P450 17-hydroxylase/lyase antibody, cytochrome P450 family 17 subfamily A member 1 L homeolog antibody, cytochrome P450 family 17 subfamily A member 1 antibody, cytochrome P-450 17 alpha-hydroxylase/C17,20-lyase antibody, cytochrome P450, family 17, subfamily a, polypeptide 1 antibody, cytochrome P450c17 antibody, CpipJ_CPIJ010537 antibody, CpipJ_CPIJ010543 antibody, PTRG_02047 antibody, cyp17a1 antibody, cyp17 antibody, cyp17a1.L antibody, CYP17A1 antibody, Cyp17a1 antibody
    Background
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.

    Cellular Localization: Membrane , Membrane, Single-pass membrane protein , Membrane , Membrane
    Molecular Weight
    57 kDa
    Gene ID
    1586
    Pathways
    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin
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