CYP17A1 antibody (AA 201-507)

Catalog No. ABIN7444547

The Rabbit Polyclonal anti-CYP17A1 antibody (ABIN7444547) specifically detects CYP17A1 in WB, IHC, ICC and IP. The antibody is reactive with Rat samples.

Quick Overview for CYP17A1 antibody (AA 201-507) (ABIN7444547)

Target: CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP17A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Product Details anti-CYP17A1 Antibody

Binding Specificity: AA 201-507

Purpose: Polyclonal Antibody to Cytochrome P450 17A1 (CYP17A1)

Specificity: The antibody is a rabbit polyclonal antibody raised against CYP17A1. It has been selected for its ability to recognize CYP17A1 in immunohistochemical staining and western blotting.

Cross-Reactivity: Human

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Cytochrome P450 17A1 (CYP17A1) corresdonding to Thr201~Thr507

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.01-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for CYP17A1

Target: CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))

Alternative Name: CYP17A1

Background: S17aH, CPT7, P450C17, 17-Alpha-Hydroxylase, 17-alpha-hydroxyprogesterone aldolase/17,20-Lyase, Steroid 17-alpha-monooxygenase, Cytochrome P450,Family 17,Subfamily A,Polypeptide 1

UniProt: P11715

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin