SREBF1 antibody (AA 38-201)

Catalog No. ABIN7170778

Product Details anti-SREBF1 Antibody

Target: SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))

Binding Specificity: AA 38-201

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SREBF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Sterol regulatory element-binding protein 1 protein (38-201AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SREBF1

Target: SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))

Alternative Name: SREBF1 (SREBF1 Products)

Background:

Background: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway (By similarity). Binds to the sterol regulatory element 1 (SRE-1) (5\\\'-ATCACCCCAC-3\\\'). Has dual sequence specificity binding to both an E-box motif (5\\\'-ATCACGTGA-3\\\') and to SRE-1 (5\\\'-ATCACCCCAC-3\\\').

Aliases: ADD 1 antibody, bHLHd1 antibody, Class D basic helix-loop-helix protein 1 antibody, D630008H06 antibody, Processed sterol regulatory element-binding protein 1 antibody, SRBP1_HUMAN antibody, SREBF 1 antibody, SREBF1 antibody, SREBP 1 antibody, SREBP 1c antibody, SREBP-1 antibody, SREBP1 antibody, Sterol regulatory element binding protein 1 antibody, Sterol Regulatory Element Binding Transcription Factor 1 / Protein 1 antibody, Sterol regulatory element binding transcription factor 1 antibody, Sterol regulatory element-binding transcription factor 1 antibody

UniProt: P36956

Pathways: AMPK Signaling, Caspase Cascade in Apoptosis, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha