SREBF1 antibody (Middle Region)

Catalog No. ABIN926950

This Rabbit Polyclonal antibody specifically detects SREBF1 in WB and IHC. It exhibits reactivity toward Human, Rat, Mouse, Pig and Cow.

Quick Overview for SREBF1 antibody (Middle Region) (ABIN926950)

Target: SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))

Reactivity: Human, Rat, Mouse, Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SREBF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SREBF1 Antibody

Binding Specificity: Middle Region

Cross-Reactivity: Rat (Rattus), Mouse (Murine), Cow (Bovine), Pig (Porcine)

Purification: Purified

Immunogen: SREBF1 antibody was raised in rabbit using the middle region of SREBF1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

SREBF1 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this SREBF1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for SREBF1

Target: SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))

Alternative Name: SREBF1

Background: SREBF1 is a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Synonyms: Polyclonal SREBF1 antibody, Anti-SREBF1 antibody, sterol regulatory element binding transcription factor 1 antibody, SREBP1 antibody.

Pathways: AMPK Signaling, Caspase Cascade in Apoptosis, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha