TLE1 antibody (AA 501-770)

Catalog No. ABIN7172790

Product Details anti-TLE1 Antibody

Target: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Binding Specificity: AA 501-770

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLE1 antibody is un-conjugated

Application: ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Transducin-like enhancer protein 1 protein (501-770AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TLE1

Target: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Alternative Name: TLE1 (TLE1 Products)

Background:

Background: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

Aliases: E(Sp1) homolog antibody, Enhancer of split groucho 1 antibody, Enhancer of split groucho like protein 1 antibody, Enhancer of split groucho-like protein 1 antibody, ESG antibody, ESG1 antibody, GRG1 antibody, TLE1 antibody, TLE1_HUMAN antibody, Transducin like enhancer of split 1 (E(sp1) homolog Drosophila) antibody, Transducin like enhancer of split 1 antibody, Transducin like enhancer of split 1 homolog of Drosophila E(sp1) antibody, Transducin like enhancer protein 1 antibody, Transducin-like enhancer protein 1 antibody

UniProt: Q04724

Pathways: WNT Signaling, SARS-CoV-2 Protein Interactome