Myosin IC antibody (AA 804-1063)
Quick Overview for Myosin IC antibody (AA 804-1063) (ABIN7174944)
Target
See all Myosin IC (MYO1C) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 804-1063
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Cross-Reactivity
- Human
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Purification
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Unconventional myosin-Ic protein (804-1063AA)
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Isotype
- IgG
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Application Notes
- Recommended dilution: IHC:1:20-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Myosin IC (MYO1C)
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Alternative Name
- MYO1C
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Background
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Background: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane. Component of the hair cell\\\'s (the sensory cells of the inner ear) adaptation-motor complex. Acts as a mediator of adaptation of mechanoelectrical transduction in stereocilia of vestibular hair cells. Binds phosphoinositides and links the actin cytoskeleton to cellular membranes.
Aliases: MMI beta antibody, MMI-beta antibody, MMIb antibody, MYO1C antibody, MYO1C_HUMAN antibody, Myosin I beta antibody, Myosin Ic antibody, Myosin-Ic antibody, MYR2 antibody, NMI antibody, Nuclear myosin I antibody
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UniProt
- O00159
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Pathways
- Platelet-derived growth Factor Receptor Signaling
Target
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