FAIM3 antibody (AA 18-262) (HRP)

Catalog No. ABIN7177188

The Rabbit Polyclonal anti-FAIM3 antibody has been validated for ELISA. It is suitable to detect FAIM3 in samples from Mouse.

Quick Overview for FAIM3 antibody (AA 18-262) (HRP) (ABIN7177188)

Target: FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAIM3 antibody is conjugated to HRP

Application: ELISA

Product Details anti-FAIM3 Antibody (HRP)

Binding Specificity: AA 18-262

Cross-Reactivity: Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Mouse Fas apoptotic inhibitory molecule 3 protein (18-262AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FAIM3

Target: FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))

Alternative Name: Fcmr

Background:

Background: May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.

Aliases: Fcmr antibody, Faim3 antibody, TosoFas apoptotic inhibitory molecule 3 antibody, IgM Fc fragment receptor antibody, Regulator of Fas-induced apoptosis Toso antibody

UniProt: A1KXC4