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P4HB antibody (AA 20-509)

P4HB Reactivity: Mouse ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7177782
  • Target See all P4HB Antibodies
    P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
    Binding Specificity
    • 21
    • 19
    • 15
    • 12
    • 11
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-509
    Reactivity
    • 108
    • 73
    • 65
    • 21
    • 20
    • 18
    • 18
    • 16
    • 16
    • 14
    • 10
    • 10
    • 7
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    Mouse
    Host
    • 120
    • 25
    • 2
    Rabbit
    Clonality
    • 111
    • 36
    Polyclonal
    Conjugate
    • 63
    • 16
    • 15
    • 9
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This P4HB antibody is un-conjugated
    Application
    • 114
    • 69
    • 45
    • 44
    • 43
    • 35
    • 17
    • 14
    • 13
    • 13
    • 13
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Mouse
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Mouse Protein disulfide-isomerase protein (20-509AA)
    Isotype
    IgG
    Top Product
    Discover our top product P4HB Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
    Alternative Name
    P4hb (P4HB Products)
    Background

    Background: This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP

    Aliases: P4hb antibody, Pdia1Protein disulfide-isomerase antibody, PDI antibody, EC 5.3.4.1 antibody, Cellular thyroid hormone-binding protein antibody, Endoplasmic reticulum resident protein 59 antibody, ER protein 59 antibody, ERp59 antibody, Prolyl 4-hydroxylase subunit beta antibody, p55 antibody

    UniProt
    P09103
    Pathways
    Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism
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