ITGAL antibody (PE)
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- Target See all ITGAL Antibodies
- ITGAL (Integrin alpha-L (ITGAL))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ITGAL antibody is conjugated to PE
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Application
- Flow Cytometry (FACS), ELISA, Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- Affinity purified
- Immunogen
- Recombinant Protein
- Isotype
- IgG1, IgG1 kappa
- Top Product
- Discover our top product ITGAL Primary Antibody
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- Application Notes
- Recommended dilution:IF:1:100-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Phosphate-buffered solution, pH 7.4, containing 0.09 % sodium azide and 0.2 % (w/v) BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- ITGAL (Integrin alpha-L (ITGAL))
- Alternative Name
- ITGAL (ITGAL Products)
- Background
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Background: 4A122 reacts with CD11a, a 180 kDa molecule. CD11a is the a chain of the leukocyte function associated antigen-1 (LFA-1a), and is expressed on all leukocytes including T and B cells, monocytes, and granulocytes, but is absent on non-hematopoietic tissue and human platelets. CD11/CD18 (LFA-1), a member of the integrin subfamily, is a leukocyte adhesion receptor that is essential for cell-to-cell contact, such as lymphocyte adhesion, NK and T-cell cytolysis, and T-cell proliferation. CD11/CD18 is also involved in the interaction of leucocytes with endothelium.*CD11a antibody has been used to reduces graft failure for bone marrow grafts in immunodeficient children. This clone is cross reactive with non-human primate.1. Schlossman. S et al. (1995) Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York.2. Lub M et al. (1995) Immunol. Today 16:479.3. Sanchez-Mateos P et al. (1996) Cancer Biol. 7:99.
Aliases: N/A
- UniProt
- P20701
- Pathways
- Activated T Cell Proliferation, Integrin Complex
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