SRI antibody (AA 32-116) (Biotin)
SRI
Reactivity: Staphylococcus aureus
ELISA
Host: Rabbit
Polyclonal
Biotin
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- Target See all SRI Antibodies
- SRI (Sorcin (SRI))
- Binding Specificity
- AA 32-116
- Reactivity
- Staphylococcus aureus
- Host
- Rabbit
- Clonality
- Polyclonal
- Conjugate
- This SRI antibody is conjugated to Biotin
- Application
- ELISA
- Cross-Reactivity
- Staphylococcus aureus
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Staphylococcus aureus Staphylococcal complement inhibitor protein (32-116AA)
- Isotype
- IgG
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SRI (Sorcin (SRI))
- Alternative Name
- scn
- Background
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Background: Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation. The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium. Also prevents C5a-induced neutrophil responses.
Aliases: scn antibody, SA1754 antibody, Staphylococcal complement inhibitor antibody, SCIN antibody
- UniProt
- Q99SU9
- Pathways
- Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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