alpha Adducin antibody (Ser726)

Catalog No. ABIN7179967

This anti-alpha Adducin antibody is a Rabbit Polyclonal antibody detecting alpha Adducin in WB, IHC, ELISA and IF. Suitable for Human.

Quick Overview for alpha Adducin antibody (Ser726) (ABIN7179967)

Target: alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha Adducin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-alpha Adducin Antibody

Binding Specificity: Ser726

Cross-Reactivity: Human, Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human ADD1 around the phosphorylation site of serine 726 (T-P-S(p)-F-L).

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for alpha Adducin

Target: alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

Alternative Name: ADD1

Background:

Background: Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.

Yun Sok Lee, Mol. Cell. Biol., Jan 2007, 27: 438 - 452.
Kang Ho Kim, J. Biol. Chem., Dec 2004, 279: 51999 - 52006.
Marc Foretz, Mol. Cell. Biol., May 1999, 19: 3760 - 3768.
Jae Bum Kim, J. Clin. Invest., Jan 1998, 101: 1.

Aliases: ADD A antibody, ADD1 antibody, ADDA antibody, ADDA_HUMAN antibody, Adducin 1 (alpha) antibody, Alpha adducin antibody, Alpha-adducin antibody, Erythrocyte adducin alpha subunit antibody, Erythrocyte adducin subunit alpha antibody, MGC3339 antibody, MGC44427 antibody, OTTHUMP00000151163 antibody, OTTHUMP00000151164 antibody, OTTHUMP00000151165 antibody, OTTHUMP00000218664 antibody, OTTHUMP00000218665 antibody

UniProt: P35611

Pathways: Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling