ATP1A1 antibody (Ser23)

Catalog No. ABIN7179977

This Rabbit Polyclonal antibody specifically detects ATP1A1 in WB, ELISA and IF. It exhibits reactivity toward Rat.

Quick Overview for ATP1A1 antibody (Ser23) (ABIN7179977)

Target: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP1A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-ATP1A1 Antibody

Binding Specificity: Ser23

Cross-Reactivity: Human, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human ATP1alpha1/Na+K+ ATPase1 around the phosphorylation site of serine 23 (K-K-S(p)-K-K).

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IF:1:100-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ATP1A1

Target: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Alternative Name: Atp1a1

Background:

Background: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.

Shull G.E., Biochemistry 25:8125-8132(1986).
Hara Y., J. Biochem. 102:43-58(1987).
Herrera V.L.M., J. Cell Biol. 105:1855-1865(1987).

Aliases: Atp1a1Sodium/potassium-transporting ATPase subunit alpha-1 antibody, Na(+)/K(+) ATPase alpha-1 subunit antibody, EC 7.2.2.13 antibody, Sodium pump subunit alpha-1 antibody

UniProt: P06685

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Proton Transport, Ribonucleoside Biosynthetic Process