DMGDH antibody (C-Term)

Catalog No. ABIN7180160

This Rabbit Polyclonal antibody specifically detects DMGDH in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for DMGDH antibody (C-Term) (ABIN7180160)

Target: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DMGDH antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DMGDH Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human DMGDH.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DMGDH

Target: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Alternative Name: DMGDH

Background:

Background: This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.

Binzak B.A., Mol. Genet. Metab. 69:181-187(2000).
Binzak B.A., Am. J. Hum. Genet. 68:839-847(2001).
Moolenaar S.H., Clin. Chem. 45:459-464(1999)

Aliases: Dimethylglycine dehydrogenase antibody, Dimethylglycine dehydrogenase, mitochondrial antibody, Dmgdh antibody, M2GD_HUMAN antibody, ME2GLYDH antibody, mitochondrial antibody

UniProt: Q9UI17