ZDHHC7 antibody (C-Term)

Catalog No. ABIN7180292

This Rabbit Polyclonal antibody specifically detects ZDHHC7 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for ZDHHC7 antibody (C-Term) (ABIN7180292)

Target: ZDHHC7 (Zinc Finger, DHHC-Type Containing 7 (ZDHHC7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZDHHC7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ZDHHC7 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human ZDHHC7.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ZDHHC7

Target: ZDHHC7 (Zinc Finger, DHHC-Type Containing 7 (ZDHHC7))

Alternative Name: ZDHHC7

Background:

Background: Palmitoyltransferase with broad specificity. Palmitoylates SNAP25 and DLG4/PSD95. May palmitoylate GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3) and thereby regulate their synaptic clustering and/or cell surface stability By similarity. Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptors.

Ota T., Nat. Genet. 36:40-45(2004).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Sjoeblom T., Science 314:268-274(2006)

Aliases: ZDHHC7 antibody, Palmitoyltransferase ZDHHC7 antibody, EC 2.3.1.225 antibody, Zinc finger DHHC domain-containing protein 7 antibody, DHHC-7 antibody

UniProt: Q9NXF8