PCGF1 antibody (AA 121-220) (Cy3)

Catalog No. ABIN713954

The Rabbit Polyclonal anti-PCGF1 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect PCGF1 in samples from Mouse and Rat.

Quick Overview for PCGF1 antibody (AA 121-220) (Cy3) (ABIN713954)

Target: PCGF1 (Polycomb Group Ring Finger 1 (PCGF1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCGF1 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PCGF1 Antibody (Cy3)

Binding Specificity: AA 121-220

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCGF1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PCGF1

Target: PCGF1 (Polycomb Group Ring Finger 1 (PCGF1))

Alternative Name: PCGF1

Background:

Synonyms: PCGF1, Nervous system Polycomb-1, NSPc1, Polycomb group RING finger protein 1, RING finger protein 68, PCGF1_HUMAN, RNF68.

Background: PCGF1 is a component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin-dependent kinase inhibitor, CDKN1A. It represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element). PCGF1 als promotes cell cycle progression and also enhances cell proliferation, thus it may have a positive role in tumor cell growth.

Gene ID: 84759