ADRA2B antibody

Catalog No. ABIN7183076

This Rabbit Polyclonal antibody specifically detects ADRA2B in ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for ADRA2B antibody (ABIN7183076)

Target: ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADRA2B antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-ADRA2B Antibody

Purpose: ADRA2B Antibody

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human Adrenergic Receptor alpha-2B.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ADRA2B

Target: ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))

Alternative Name: ADRA2B

Background:

Background: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.

Lomasney J.W., Proc. Natl. Acad. Sci. U.S.A. 87:5094-5098(1990).
Weinshank R.L., Mol. Pharmacol. 38:681-688(1990).
Small K.M., J. Biol. Chem. 276:4917-4922(2001).

Aliases: ADRA2B antibody, ADRA2L1 antibody, ADRA2RL1Alpha-2B adrenergic receptor antibody, Alpha-2 adrenergic receptor subtype C2 antibody, Alpha-2B adrenoreceptor antibody, Alpha-2B adrenoceptor antibody, Alpha-2BAR antibody

UniProt: P18089

Pathways: EGFR Signaling Pathway, cAMP Metabolic Process