PKIA antibody

Catalog No. ABIN7183675

The Rabbit Polyclonal anti-PKIA antibody (ABIN7183675) specifically detects PKIA in ELISA, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for PKIA antibody (ABIN7183675)

Target: PKIA (Protein Kinase (CAMP-Dependent, Catalytic) Inhibitor alpha (PKIA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKIA antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PKIA Antibody

Purpose: PKIA Antibody

Cross-Reactivity: Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human IPKA.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PKIA

Target: PKIA (Protein Kinase (CAMP-Dependent, Catalytic) Inhibitor alpha (PKIA))

Alternative Name: PKIA

Background:

Background: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

Olsen S.R., Mol. Endocrinol. 5:1246-1256(1991).
Knoell R., Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
The MGC Project Team, Genome Res. 14:2121-2127(2004).

Aliases: PKIA antibody, PRKACN1cAMP-dependent protein kinase inhibitor alpha antibody, PKI-alpha antibody, cAMP-dependent protein kinase inhibitor antibody, muscle/brain isoform antibody

UniProt: P61925

Pathways: Myometrial Relaxation and Contraction