PDZD2 antibody

Catalog No. ABIN7183951

This anti-PDZD2 antibody is a Rabbit Polyclonal antibody detecting PDZD2 in ELISA, IHC and IF. Suitable for Human.

Quick Overview for PDZD2 antibody (ABIN7183951)

Target: PDZD2 (PDZ Domain Containing 2 (PDZD2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDZD2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PDZD2 Antibody

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human PDZD2.

Isotype: IgG

Application Details

Application Notes: IHC:1:50-1:100, IF:1:100-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PDZD2

Target: PDZD2 (PDZ Domain Containing 2 (PDZD2))

Alternative Name: PDZD2

Background:

Background: Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.

Chaib H., Cancer Res. 61:2390-2394(2001).
Nagase T., DNA Res. 4:141-150(1997).

Aliases: PDZD2 antibody, AIPC antibody, KIAA0300 antibody, PDZK3 antibody, PDZ domain-containing protein 2 antibody, Activated in prostate cancer protein antibody, PDZ domain-containing protein 3) [Cleaved into: Processed PDZ domain-containing protein 2] antibody

UniProt: O15018